Hyaluronic Acid Injections

What is Hyaluronic Acid?

Hyaluronic Acid Injections (the common brands being Monovisc, Synvisc and Durolane) are used to treat knee and other joint pain caused by osteoarthritis (OA) in patients who have already been treated with pain relievers or other treatments without satisfactory outcomes.

Hyaluronic acid is found naturally in joints and other parts of the body. In the joint, it is found in the cartilage and the synovial fluid that lubricates the joints to keep them working smoothly.

In people with arthritis, the hyaluronic acid gets thinner and it is no longer able to protect the joint. Injections of artificial hyaluronic acid into affected joints may improve the protection, similar to a top up of engine oil.

Why Consider Hyaluronic Acid Injection?

Hyaluronic acid injections help reduce the pain caused by osteoarthritis. Some patients find relief from symptoms within a few days. Full benefits usually are reached 3-5 weeks after the treatment. The peak effect is at about 8 weeks and the treatment may provide pain relief for up to 9 months. Response varies and the injections do not help everyone. If successful the injections can be repeated after 6-9 months.

Because Hyaluronic Acid is a thick medication serves to supplement your own hyaluronic acid and keep the bones from scraping against each other, the mechanism used is similar to a lubricant to help decrease inflammation and ease the pain.

For very inflamed joints, Corticosteroid injections may help to settle down the inflammation in the weeks prior to viscosupplementation. This is thought to make it more effective as inflammation probably leads to faster break-down of the hyaluronic acid molecules.

Types of Hyaluronic Acid Injection

The following medications are all types of hyaluronic acid injections:

Sodium hyaluronate (Euflexxa, Hyalgan, Supartz)
High-molecular-weight hyaluronan (Durolane, Monovisc, Orthovisc)
Hylan G-F 20 (Synvisc, Synvisc One)
Cross-linked hyaluronate (Gel-One)

Patients may have their own preference for which type to use based on past experience, but generally Durolane is a good first choice because it has a lower rate of allergic/inflammatory joint reactions. For smaller joints monovisc is a good choice.

These products are relatively expensive and average $300-500 for the injection product alone, but some health funds subsidize them.

Hyaluronic Acid Injection Treatment Protocol

In the past, multiple weekly injections were required for Viscosupplementation. With the advent of High Molecular Weight formulations- the injection stays inside the joint for much longer, and therefore a single injection is now used with up to 9 months of effect. Results indicate that the injections work well to control knee pain in particular, but many of these products now have general approval to be used in any synovial joint in the body.

To ensure accuracy, Dr Samra uses image guidance with high-resolution ultrasound to inject the hyaluronic acid directly into the affected joint. A local anaesthetic is used before the injection.

This medicine is to be administered only by or under the immediate supervision of your doctor, and all injections require a prescription.

Alternative Arthritis Treatment

Osteoarthritis (OA) is the most widespread joint disease affecting the elderly population.

A comprehensive, individualised treatment plan should always be provided.

Common non-steroidal anti-inflammatory drugs (NSAIDs), supplements of chondroitin sulphate and/or glycosaminoglycans are prescribed as non-operative treatments, but these are aimed and pain relief.

Fluid aspiration (arthrocentesis) this procedure removes some fluid from the knee. By removing excess fluid immediate relief from pain and swelling may result. This is sometimes done prior to receiving an injection of corticosteroids or hyaluronic acid.

Alternative Therapies include:

Hyaluronic Acid Injections Treatment Process

Preparation for Treatment

The patient should be counselled to ensure that the treatment is understood.

Hyaluronic Acid Injections must be ordered by the patient prior to the injection appointment.

The doctor will:

Take your medical history, including allergies or prior drug interactions
Conduct a physical examination, and
You may be asked to have a number of tests to ensure that the injections are suitable.
Advise the doctor if you take Aspirin, Anti-inflammatory or Blood-thinning medications
Skin or knee joint infections at the place where the injection is to be given
Joint effusion should be treated first before receiving this medicine.

Day of Your Treatment

Do not consume large amounts of alcohol for at least 24 hours prior to treatment,
Avoid vigorous physical activity or exercise for 24 hours,
Wear loose clothing

Injection Approach
In some cases, the doctor may recommend a local numbing medication be applied to the injection site, this also temporarily relieves pain. This can be discussed.

Pain relief with Hyaluronic Acid Injection is not immediate.

During Your Treatment

This procedure can be carried out in minutes at the doctor’s office. The patient:

Lies down, while the doctor then administers the Hyaluronic Acid Injection.
May feel a short period of discomfort during the injection that goes away quickly.

After Your Treatment

Patients are given written post-injection instructions and:

Able to walk or drive afterwards without issue,
Can return home or work the same day, and
Should rest the injected area for two or three days

Where there is local pain, the patient is advised to rest for two days before resuming normal activities.

Common Questions

If you have a specific question about your treatment, we recommend contacting the clinic.

What is Injected?

Hyaluronic acid is found naturally in joints and other parts of the body. In the joint, it is found in the cartilage and the synovial fluid that lubricates the joints to keep them working smoothly.
Does It Hurt?

Everyone experiences pain differently and has different pain thresholds. When it comes to injections, it is a relatively painless procedure, though a mild stinging sensation may be felt.
Most people compare the sensation to a quick prick or a slight pinching feeling, but it only lasts for a few seconds.

Typically Injection treatments require no anaesthetic, however, a topical anaesthetic can be used if needed.
What if I Am Pregnant?

It is not recommended to receive injectable treatments while pregnant, as the risks are uncertain due to the lack of information available about the effect on the fetus.

For more information please call us on and request to speak with one of our medically-trained registered doctor or nurse.
What if I am Not 18 years old?

We do not treat anyone under the age of 18 for injectables without a parent or guardian to discuss and approve of the treatment.

How Much Will I Need?

To determine the correct dosage you need to book in for a consultation with our doctor.

With regular treatments, the dosage can be reduced.
Can I Bring My Child?

Whilst we all love children, in the interest of health and safety, children cannot accompany patients in the treatment rooms or be supervised by staff.

Thank you for your understanding.
Possible Risk or Complications of Hyaluronic Acid Injections
Side effects of hyaluronic acid injections are not common. Most are limited to the site of injection and do not last long. Local side effects may include:
- redness and tenderness at the site of the injection
- increased stiffness, swelling or warmth inflammation for up to 48 hours following the injection.
These local reactions may be treated by resting and applying ice to the injected area or by simple pain relievers. Less common side effects are:
- Allergy rashes, hives, itching, flushing and swelling of the face, tongue or throat, chest tightness and shortness of breath.
- Other side effects that have been observed include headache, muscle pain, nausea, sore throat and flu-like symptoms.
Hyaluronic acid may be used with other arthritis medicines including:
- steroid medicines such as prednisolone or cortisone injections into the joint
- anti-inflammatory medicines (NSAIDs) such as naproxen, ibuprofen
- simple pain-relieving medicines such as paracetamol.
Stages of Recovery after Hyaluronic Acid Injections

There is usually no recovery time associated with Hyaluronic Acid Injections.

The local soreness in the area goes away quickly. The doctor may advise you to schedule a follow-up appointment after three months of the treatment.

Some areas may need more strict rest for a longer period depending on the condition being treated. Your doctor will discuss this with you prior to the injection.